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Does B12 Help with Memory?

Vitamin B12 helps to synthesize and maintain the protective layer of nerve cells. It helps prevent brain atrophy which is a major cause of memory loss. B12 also aids in the production of essential amino acids that improve memory and brain function.

So, the answer is a resounding “Yes.” Vitamin B12 helps with memory.

Vitamin B12 is a micronutrient that is important for maintaining brain health. So, its deficiency leads to cognitive changes that include memory decline.

How does vitamin B12 help with memory, and are there B12 supplements to help with memory?

Read on to find answers to these questions.

How does B12 help with memory?

Vitamin B12 helps memory in different ways that include:

  • Maintaining the protective layer of nerve cells

  • Helping in the prevention of brain atrophy

  • Assisting in the production of amino acids crucial to neurological development

Let’s explore these concepts deeper.

B12 maintains the protective layer of nerve cells

Vitamin B12 is crucial to the proper functioning of nerve cells (which are fundamental units of the brain and nervous system).

B12 helps synthesize and maintain myelin, a fatty tissue that protects nerve cells, allowing them to properly function in sending nerve signals back and forth between the brain and the rest of the body.

Vitamin B12 deficiency can affect the maintenance of myelin. Damage to myelin sheaths can cause nerve signals to slow down or stop, resulting in neurological disorders like dementia (or memory loss).

Vitamin B12 prevents brain atrophy

Vitamin B12 plays an important role in preventing brain atrophy (the loss of brain neurons) which is a leading cause of dementia (memory loss).

Vitamin B12 is a cofactor in the metabolic process that converts methylmalonic acid (MMA) to succinyl-CoA. Without this process, MMA builds up, and this can reduce total brain volume. A reduction of brain volume brings about a host of cognition problems, including memory loss.

B12 helps in the synthesis of essential amino acids

In another important metabolic process, vitamin B12 is used (along with folic acid) to convert homocysteine to methionine, an amino acid crucial to neurological development.

Thus, vitamin B12 helps in the proper functioning of the methionine cycle towards protecting the brain from damage.

Now that you understand the role of B12 in memory, let’s look at some excellent B12 supplements that you can use to ensure brain health.

Best B12 supplements for memory

B12 is available naturally in food like meat, fish, eggs, and dairy products. It’s also available in breakfast cereals fortified with vitamin B12.

However, you may need B12 supplements to maintain appropriate levels of this important vitamin. Supplementation is useful, especially if your body can’t easily absorb vitamin B12 from food sources or if you’re a vegan.

There are important things to consider when choosing B12 supplements, including the B12 form, ingredient lists, dosage, ease of use, and manufacturing practices.

Considering these factors and more, here are some of the best vitamin B12 supplements for memory.

1. Why Not Natural B12 Liquid Supplement

Why Not Natural is by far our #1 B12 supplement. It leads the pack for many reasons.

First, it is made from organic ingredients (organic vegetable glycerin, organic cherry flavor, citrus extract, and purified water). It has no artificial additives.

Secondly, it features methylcobalamin which is the most absorbable B12 form. So, it is easy for your body to use.

Thirdly, it contains 5000 mcg per ml, which is almost double what you’ll get with many other supplements. This gives you more for your money. Keeping in mind that your body absorbs about 2% of the total B12 you take, you need to consume more.

Also, the Why Not Natural B-12 supplement comes with a graduated glass dropper which makes it easy to measure your B-12 dosage. There’s no reason not to like the Why Not Natural Vitamin B12 supplement.

2. Superior Source No Shot Vitamin B12 Dietary Supplement

If you want your vitamin B12 in tablet form, you can’t go wrong with this supplement.

First, these are sublingual instant dissolve tablets. There are no large pills to swallow. Just put the tiny tablet under your tongue, and it dissolves immediately, allowing for immediate absorption and utilization.

Also, the supplement features methylcobalamin which doesn’t need to be converted to be immediately utilized. So, you will feel more energized and have a sharper focus immediately after taking it.

The Superior Source No Shot Vitamin B12 supplement also features pure ingredients. The supplements are gluten-free and sugar-free, and there are no additives or preservatives whatsoever.

With its potency, pure formulation, and quick-dissolving of tablets for absorption and utilization, this is among the best tablet B12 supplements.

Beware that this supplement will color your tongue and teeth bright red immediately after taking it. Thankfully, the bright red color goes off quickly.

3. Jarrow Formulas Methyl B-12 Supplement

This vitamin B12 supplement is available as chewable tablets. The supplement echoes Jarrow Formulas’ mission to put science first. It uses methyl B12, which is better absorbed and retained by the body than other forms of B12.

You can also be assured of potency and purity when choosing Jarrow Formulas’ Methyl B12 supplement. Each chewable tablet contains 5000mcg of B12. It is gluten-free and ideal for vegetarians.

Jarrow Formulas Methyl B12 supplements tick many of the right boxes. We especially liked that it gives a good dose of B12. The bottle contains 60 chewable tablets, with each tablet providing 5,000 mcg of B12. You can say it’s as potent as our #1 B12 supplement (Why Not Natural). However, it’s not as pure, as it contains additives like xylitol and magnesium stearate.

4. Vitafusion Extra Strength Vitamin B12 Gummies

Here, you have vitamin B12 fused into delicious gummies. If you like chewing gummies, you should be getting your B12 dose while at it. The Vitafusion Extra Strength B12 supplement ensures that.

It may be called an extra-strength B12 supplement, but B12 is also important for maintaining the brain and spinal cord functions, so it is also an excellent B12 supplement for memory.

Vitafusion believes they can fuse that taste and nutrition to deliver the best vitamin experience, which is seen in the taste of their B12 supplement gummies. They taste like cherry gummy candies and are not sticky to the mouth.

If you don’t like the taste or texture of melting B12 supplements tablets, Vitafusion may be for you.

Also, these supplements contain no artificial sweeteners, no high fructose corn syrup, no dyes, no gluten.

However, each bottle has 90 gummies, and it takes 2 to provide you with 3,000 mcg of B12. Thus, the bottle amounts to 45 servings of 3,000 mcg of B12. By comparison, the Why Not Natural B12 supplement provides 60 servings of 5,000 mcg of B12.

5. MaryRuth Organic Liquid Vitamin B12 Spray

MaryRuth Vitamin B12 spray allows you to take your supplements with simple squirts conveniently. If swallowing pills or chewing gummies are a chore, the spray bottle of MaryRuth will be appealing. Additionally, the berry spray is tasty.

The supplement is specifically designed to provide neuroprotective support and maintain cognitive function, so it’s one of the best B12 supplements for memory.

It uses methyl B12 that has superior bioavailability. It has a clean ingredient list, and it’s free of common allergens and artificial flavors. There are many things to like about this methyl B12 liquid spray supplement, including that it’s certified organic and acceptable for vegans.

However, while each bottle comes with 120 servings, the recommended serving (2 sprays) provides only 1500 mcg of vitamin B12. So, the bottle provides 60 servings of 1,500 mcg of vitamin B12. This also falls short of the 60 servings of 5,000 mcg of B12 that Why Not Natural provides.


It is well documented that vitamin B12 energizes. However, a less mentioned yet critical function of B12 is that it helps memory.

It does this by helping maintain the myelin sheaths that protect nerve cells, preventing the build-up of methylmalonic acid that causes brain atrophy, and assisting in the production of methionine that improves memory and brain function.

Especially given how it helps memory, vitamin B12 is a nutrient that you need.

You can take vitamin B12 from animal-based foods or supplements. While there are different B12 supplements out there, one that stands out is the Why Not Natural B12 Dietary supplement.

Why Not Natural supplement is a symbol of purity and potency, which features a clean ingredient list and 60 potent 5,000 mcg liquid doses of the easily absorbable methyl B12.

No wonder it’s the #1 vitamin B12 supplement. Get Why Not Natural B12 supplement today for improved memory.

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